PGT-A is associated with reduced cumulative live birth rate in donor oocyte IVF cycles: An analysis of 18,599 donor cycles reported to SART CORS

January 2025Articles
Gingold J, Kucherov A, Fazzari M, Lieman H, Ball GD, Doody K, Jindal S. Fertility and Sterility 123:50-60, 2025. PMID: 39128672. WHY WAS THIS STUDY CONDUCTED? To evaluate the impact of preimplantation genetic testing for aneuploidy (PGT-A) on first transfer live birth rate (LBR) and cumulative LBR (CLBR) in donor oocyte in vitro fertilization (IVF) [...]

Trophectoderm biopsy is associated with lower risks of moderate to extreme prematurity and low birth weights – a national registry cohort study of singleton live births from frozen-thawed blastocyst transfers.

December 2024Articles
Liu A, Shah T, Wu H, Lieman H, Singh M, Pollack S, Jindal S. AJOG 231:636:e1-9, 2024. PMID: 39029546. WHY WAS THIS STUDY CONDUCTED? Safety data on embryo biopsy for preimplantation genetic testing has been conflicting because of heterogeneous cohorts and the study of out-of-date assisted reproductive techniques. We aimed to address this gap in [...]

Recruiting and cultivating future leaders in laboratory science.

August 2024Articles
Bartolucci A, Alouf C, Angle M, Jindal, SK. Invited Review, Current Opinion in Obstetrics and Gynecology 36:218-222, 2024. PMID: 38695603. WHY WAS THIS STUDY CONDUCTED? Stakes have never been higher or the need greater for the recruitment and cultivation of leaders in laboratory science to navigate the direction of IVF. KEY FINDINGS Recruitment of scientists [...]

Protocol change improves live birth and recurrent cycle cancellation rates after a previous IVF cycle cancellation: an analysis of 13,000 autologous cycles reported to SART CORS.

May 2024Articles
Kahn J, Wu H, Gerber R, Shah T, Lieman H, Pollack SE, Singh M, Jindal S. Human Reproduction 39:1504-11, 2024. PMID: 38783613. WHY WAS THIS STUDY CONDUCTED? After an IVF cycle cancellation, does changing the stimulation protocol affect the odds of live birth and recurrent cancellation in the subsequent cycle? KEY FINDINGS Using a large [...]

Comparing reproductive outcomes between conventional IVF and non-recommended ICSI in autologous single embryo transfer cycles: a SART CORS study

March 2024Articles
Gingold JA, Wu H, Lieman H, Singh M, Jindal S. Fertility and Sterility Reports 5:23-32, 2024. PMID: 38524206. WHY WAS THIS STUDY CONDUCTED? To compare clinical outcomes between non-indicated intracytoplasmic sperm injection (ICSI) and conventional insemination. KEY FINDINGS Non-indicated ICSI was associated with reduced blastocyst availability in fresh cycles compared with IVF, leading to lower [...]

ASRM PC 2022 Lab Guidance

June 2022Articles

This comprehensive guidance document for lab management and operations was created by Sangita K. Jindal Ph.D. as part of her work on the ASRM practice committee and published in August 2022. It is an update to a previous document from 2008 and is used nationally by all IVF labs as best practice guidance for lab operations, quality control, lab staffing and qualifications, and staffing volumes to ensure patient safety and optimal patient care.